Non-invasive Vagus Nerve Stimulation Study

European Heart Journal (2025) - Randomized Controlled TrialView Original Study

Breakthrough Finding

Revolutionary Discovery

Just 30 minutes of daily ear stimulation for 1 week improved exercise capacity equivalent to weeks of traditional training

3.8%
VO₂ Peak
2.7%
Work Capacity
23%
Inflammation Reduction

📚 Access the Original Research

Published in the European Heart Journal, this peer-reviewed study represents a significant advancement in non-invasive neuromodulation for cardiovascular health.

DOI:10.1093/eurheartj/ehaf037
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Study Participants

Total Participants28 healthy volunteers
Gender Balance50% female, 50% male
Age Range20-63 years (mean: 34)
Completion Rate100%

Intervention Protocol

Bilateral ear stimulation
Tragus electrodes on both ears
30 minutes daily
7 consecutive days
Low intensity stimulation
Below perception threshold
Double-blind design
Sham-controlled crossover

Study Timeline

1
Baseline
Visit 1
Initial Testing
2
Week 1
Intervention
30 min daily stimulation
3
Week 2-3
Washout
2-week break
4
Week 4
Crossover
Alternate treatment

Study Reference

Ackland GL, et al. Non-invasive vagus nerve stimulation and exercise capacity in healthy volunteers: a randomized trial.

European Heart Journal (2025) 46, 1634–1644

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